超膜信号のツールキットに新たなツィストが加えられました
Mark A Lemmon1, Kathryn M Ferguson
1Department of Biochemistry & Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. mlemmon@mail.med.upenn.edu
Cell
|July 31, 2007
まとめ
結晶構造は,幹細胞因子 (SCF) がキット受容体チロシンキナーゼをダイメリゼーションを駆動することによって活性化する方法を示しています. これらの発見は,キット変異ががんの発症にどのように寄与するかにも光を当てています.
科学分野:
- バイオケミストリー バイオケミストリー
- 構造生物学 構造生物学とは
- 分子生物学は分子生物学である.
背景:
- キット受容体チロシンキナーゼは,細胞信号伝達経路において重要な役割を果たします.
- キットのシグナリングの調節不全は,様々ながんに絡み合っている.
さらに関連する動画
09:01Gain-compensation Methodology for a Sinusoidal Scan of a Galvanometer Mirror in Proportional-Integral-Differential Control Using Pre-emphasis Techniques
Published on: April 4, 2017
7.8K
09:13Implementation of a Nonlinear Microscope Based on Stimulated Raman Scattering
Published on: July 6, 2019
7.2K
関連する概念動画
Clipper Circuit
1.0K
A clipper circuit is a fundamental wave-shaping device that harnesses the unique properties of diodes to alter and control waveform characteristics. This technology is widely used in electronic devices, especially in television and radar communication systems, where it enhances waveform modulation in both transmitters and receivers.
The operation of a clipper circuit can be exemplified by analyzing a dual-clipper configuration setup that integrates two ideal diodes, each paired with a biasing...
The operation of a clipper circuit can be exemplified by analyzing a dual-clipper configuration setup that integrates two ideal diodes, each paired with a biasing...
1.0K
Even and Odd Signals
2.6K
An even signal, whether in continuous-time or discrete-time, is defined by its symmetry with its time-reversed version. Mathematically, this is represented as
2.6K
Basic Operations on Signals
1.3K
Basic signal operations include time reversal, time scaling, time shifting, and amplitude transformations. These operations are fundamental in signal processing and analysis.
Time Reversal mirrors a continuous-time signal about the vertical axis at t=0. This is achieved by substituting t with −t. For example, if a signal x(t) is considered, the time-reversed signal is x(−t). This operation can be graphically represented, showing the mirrored signal.
Time Reversal mirrors a continuous-time signal about the vertical axis at t=0. This is achieved by substituting t with −t. For example, if a signal x(t) is considered, the time-reversed signal is x(−t). This operation can be graphically represented, showing the mirrored signal.
1.3K
Deconvolution
764
Deconvolution, also known as inverse filtering, is the process of extracting the impulse response from known input and output signals. This technique is vital in scenarios where the system's characteristics are unknown, and they must be inferred from the observable signals.
Deconvolution involves several mathematical techniques to derive the impulse response. One common approach is polynomial division. In this method, the input and output sequences are treated as coefficients of...
Deconvolution involves several mathematical techniques to derive the impulse response. One common approach is polynomial division. In this method, the input and output sequences are treated as coefficients of...
764
Reconstruction of Signal using Interpolation
920
Signal processing techniques are essential for accurately converting continuous signals to digital formats and vice versa. When a continuous signal is sampled with a period T, the resulting sampled signal exhibits replicas of the original spectrum in the frequency domain, spaced at intervals equal to the sampling frequency. To handle this sampled signal, a zero-order hold method can be applied, which creates a piecewise constant signal by retaining each sample's value until the next...
920
Transformations of Functions III
304
Transformations modify the graphical representation of a function without changing its fundamental form. One common transformation is reflection, which flips the graph across a designated axis. When the vertical coordinates of all points are multiplied by the negative one, the entire graph is mirrored over the horizontal axis. This transformation reverses the vertical orientation of peaks and troughs, akin to signal inversion in electrical systems, where a waveform is flipped, but the timing of...
304
