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Updated: Jul 5, 2026

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo
08:19

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo

Published on: July 20, 2019

TSC1のIKKβ抑制は,mTOR経路経由で炎症と腫瘍血管新生を結びつける

Dung-Fang Lee1, Hsu-Ping Kuo, Chun-Te Chen

  • 1Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

Cell
|August 19, 2007
PubMed
まとめ

腫瘍死滅因子アルファ (TNFalpha) は,炎症と癌を関連付けています. この研究では,IKKβ phosphorylates TSC1がmTORを活性化し,腫瘍の成長と血管新生を促進し,潜在的ながん介入標的を提供することを明らかにしました.

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Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants07:38

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants

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