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Updated: Jul 12, 2026

Resin-Assisted Capture Coupled with Isobaric Tandem Mass Tag Labeling for Multiplexed Quantification of Protein Thiol Oxidation
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Resin-Assisted Capture Coupled with Isobaric Tandem Mass Tag Labeling for Multiplexed Quantification of Protein Thiol Oxidation

Published on: June 21, 2021

PKGIa内のシステイン・レドックスセンサーは,酸化物質誘発活性化を可能にします

Joseph R Burgoyne1, Melanie Madhani, Friederike Cuello

  • 1Department of Cardiology, Cardiovascular Division, King's College London, Rayne Institute, St. Thomas' Hospital, London SE1 7EH, UK.

Science (New York, N.Y.)
|August 25, 2007
PubMed
まとめ

グアニルサイクラゼ依存タンパク質キナーゼ (PKG) は,酸化還元センサーとして作用します. 酸化はPKGを活性化させ,基板の親和性を高め,窒素酸化物とcGMPから独立して細胞機能を調節します.

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