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Updated: Jul 12, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

Hzfは,p53トランザクティベーションを調節することによって,遺伝子毒性ストレスに対する細胞生存を決定する

Sanjeev Das1, Lakshmi Raj, Bo Zhao

  • 1Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.

Cell
|August 28, 2007
PubMed
まとめ

血液形成性亜鉛指 (Hzf) は,p53腫瘍抑制体の遺伝子毒性ストレスへの反応を調節する. Hzfは細胞サイクル停止とDNA修復を促進し,細胞運命を決定する上で極めて重要なアポトーシスを予防します.

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