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Updated: Jul 5, 2026

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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Published on: April 26, 2017

hCAS/CSE1Lはクロマチンと結合し,特定のp53標的遺伝子の発現を調節する

Tomoaki Tanaka1, Shuichi Ohkubo, Ichiro Tatsuno

  • 1Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

Cell
|August 28, 2007
PubMed
まとめ

人間の細胞アポトーシス感受性タンパク質 (hCAS/CSE1L) は,特定の遺伝子プロモーターと結合し,p53媒介の転写とアポトーシスなどの細胞結果に影響を与えます. そのダウンレギュレーションは遺伝子発現とヒストンのメチル化に影響します.

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