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Proofreading01:43

Proofreading

Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
Proofreading01:43

Proofreading

Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
Termination of Translation01:44

Termination of Translation

The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
Proofreading01:31

Proofreading

Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase Enzyme
Variance01:15

Variance

The deviations show how spread out the data are about the mean. A positive deviation occurs when the data value exceeds the mean, whereas a negative deviation occurs when the data value is less than the mean. If the deviations are added, the sum is always zero. So one cannot simply add the deviations to get the data spread. By squaring the deviations, the numbers are made positive; thus, their sum will also be positive.The standard deviation measures the spread in the same units as the data.

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Updated: Jul 1, 2026

Molecular Evolution of the Tre Recombinase
12:02

Molecular Evolution of the Tre Recombinase

Published on: May 29, 2008

Erratum Erratum エラトゥーム エラトゥーム

    Science (New York, N.Y.)
    |August 7, 1987
    PubMed
    まとめ

    T-evenファグに関するレポートの訂正が発行されました. この研究では,nrdBのイントロンが変数的に発生し,これらのファグゲノム内の移動性を示唆していることが判明しました.

    科学分野:

    • 分子生物学は分子生物学である.
    • ウイルス学 ウイルス学 ウイルス学
    • 遺伝学 遺伝学とは

    背景:

    • ペデルセン・レーンとベルフォートによる報告書"T-evenファージにおけるnrdBイントロンの変数発生はイントロンの移動性を示唆する"には印刷ミスが含まれていた.
    • 正確な科学的報告は,分子生物学とウイルス学における研究成果の普及に不可欠です.

    研究 の 目的:

    • オリジナルレポートから訂正された文を提供するために.
    • T-evenファージにおけるイントロンホモロジーと実験方法の正確な理解を確保する.

    主な方法:

    • 公開された報告書内の特定の文の訂正.
    • プレメッセンジャーRNA (pre-mRNA) のハイブリド化とデデオキシプライマー拡張分析への参照.
    • フィギュア・レジェンドで使用されているオリゴヌクレオチド探査機の記述の明確化.

    主要な成果:

    • tdイントロンは,T-evenファグ全体で同類である.
    • 実験的検証には,ハイブリダイゼーションとプライマー拡張分析が含まれていました.
    • オリゴヌクレオチドプローブは,実験再現性のために明確に定義されました.

    さらに関連する動画

    The Lambda Select cII Mutation Detection System
    07:08

    The Lambda Select cII Mutation Detection System

    Published on: April 26, 2018

    Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
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    Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

    Published on: September 20, 2024

    関連する実験動画

    Last Updated: Jul 1, 2026

    Molecular Evolution of the Tre Recombinase
    12:02

    Molecular Evolution of the Tre Recombinase

    Published on: May 29, 2008

    The Lambda Select cII Mutation Detection System
    07:08

    The Lambda Select cII Mutation Detection System

    Published on: April 26, 2018

    Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
    05:46

    Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

    Published on: September 20, 2024

    結論:

    • 修正された情報は,T-evenファグにおけるtdイントロンの同質性を明らかにする.
    • 正確な方法論の記述は,イントロンの移動性に関する発見を検証するために不可欠です.