塩の摂取量の変化がチンパンジーの血圧に影響する:ヒトの人口への影響
Paul Elliott1, Lesley L Walker, Mark P Little
1Department of Epidemiology and Public Health, Imperial College London, Faculty of Medicine, St. Mary's Campus, Norfolk Place, London W2 1PG, UK. p.elliott@imperial.ac.uk
Circulation
|September 6, 2007
まとめ
チンパンジーの食中のナトリウム摂取量を減らすことで,血圧が著しく低下した. これらの発見は,ヒトのナトリウム消費量を減らすための公衆衛生イニシアチブをサポートしています.
科学分野:
- 霊長類の生理学について
- 心血管研究に関する研究.
- 栄養科学とは,栄養科学である.
背景:
- 以前の研究では,塩の摂取量が多くて,チンパンジーの血圧が上昇することが示されていた.
- チンパンジーのわずかなナトリウム減少の効果は,以前は知られていませんでした.
研究 の 目的:
- チンパンジーの血圧に対するナトリウム摂取量の減少の影響を調査するために.
- ナトリウム減少のための人間の公衆衛生戦略を伝えるために.
主な方法:
- ガボンとテキサスのチンパンジーのナトリウム摂取量は,数年にわたって変化していた.
- 食事中のナトリウム濃度は変化し,最低35mmol/dまで減少しました.
- 血圧は,ナトリウム摂取量に関連してモニタリングされました.
主要な成果:
- 減少したナトリウム摂取量は,シストリック,ダイアストリック,および平均動脈血圧の低下と両箇所で有意に関連していました.
- 血圧の低下は,低ナトリウム摂取量 (35 mmol/dまで) でさえも観察されました.
- ベースラインの血圧の上昇は,ナトリウム減少後のより大きな血圧低下と相関する.
結論:
- 食事中のナトリウム摂取量をわずかに減らすことは,チンパンジーの血圧を効果的に低下させる.
- 発見は,人類におけるナトリウム消費量を減らすための公衆衛生の努力を支持しています.
- チンパンジーは,人間と近い親戚であり,食事中のカルシウムとカリウムの摂取量が類似しているため,ヒトの健康に関する研究に適したモデルを提供している.
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