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Updated: Jul 11, 2026

Defining Substrate Specificities for Lipase and Phospholipase Candidates
08:59

Defining Substrate Specificities for Lipase and Phospholipase Candidates

Published on: November 23, 2016

タンパク質工学による酵素・基板相互作用に対するステリック・ヒドロホビック効果の調査

D A Estell, T P Graycar, J V Miller

    Science (New York, N.Y.)
    |August 8, 1986
    PubMed
    まとめ

    サブティリシンのタンパク質工学は,ステリックおよび水害性の効果が基板特異性にどのように影響するかを明らかにしました. 水害性置換は,小さな基板の触媒効率を高め,より大きな分子からのステリック阻害は,それを大幅に減少させた.

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