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Updated: May 11, 2026

Isolation and Ex Vivo Culture of Vδ1+CD4+γδ T Cells, an Extrathymic αβT-cell Progenitor
10:33

Isolation and Ex Vivo Culture of Vδ1+CD4+γδ T Cells, an Extrathymic αβT-cell Progenitor

Published on: December 7, 2015

成熟したB細胞をT細胞に変容させ,非コミットドプロゲンテータへの脱差別化を行う

César Cobaleda1, Wolfram Jochum, Meinrad Busslinger

  • 1Research Institute of Molecular Pathology, Vienna Biocenter, Dr. Bohr-Gasse 7, A-1030 Vienna, Austria.

Nature
|September 14, 2007
PubMed
まとめ

成熟したB細胞は,Pax5遺伝子が削除され,T細胞の発達を救出し,リンパ腫を誘発する可能性があるため,未結合の原始細胞に戻ることができます. これは,微分化した細胞の意外な可塑性を明らかにします.

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In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells

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