Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Tetanus01:29

Tetanus

Tetanus is a life-threatening neurological disorder characterized by persistent muscle contractions and spastic paralysis. It is caused by Clostridium tetani, a motile, Gram-positive, rod-shaped, obligate anaerobe. These bacteria produce terminal endospores, giving them a distinctive “lollipop” or “tennis-racket” appearance. They thrive in anaerobic environments, such as those found in deep puncture wounds.Once introduced into the body, the spores germinate into vegetative cells. These cells...
Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Botulism01:22

Botulism

Botulism is a life-threatening neuroparalytic condition caused by botulinum neurotoxin, which is produced by the bacterium Clostridium botulinum, a Gram-positive, spore-forming, obligate anaerobe.In adults, the toxin enters the body in different ways: in foodborne botulism, the preformed toxin is absorbed in the intestine. In wound botulism, spores grow in injured tissue and release the toxin into the blood. Infant botulism differs mechanistically from adult forms. In infants, botulism commonly...

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Serum anti-tetanus and measles antibody titres in Ugandan children aged 4 months to 6 years: implications for vaccine programme.

Epidemiology and infection·2018
Same author

Rationing tests for drug-resistant tuberculosis - who are we prepared to miss?

BMC medicine·2016
Same author

A cluster randomized non-inferiority field trial on the immunogenicity and safety of tetanus toxoid vaccine kept in controlled temperature chain compared to cold chain.

Vaccine·2014
Same author

Ischemic cardiac events during the Department of Health and Human Services Smallpox Vaccination Program, 2003.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2008
Same author

Myocarditis, pericarditis, and dilated cardiomyopathy after smallpox vaccination among civilians in the United States, January-October 2003.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2008
Same author

Diagnosis of smear-negative tuberculosis in people with HIV/AIDS.

Lancet (London, England)·2007

関連する実験動画

Updated: Jul 11, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

妊婦と新生児のテタヌス

Martha H Roper1, Jos H Vandelaer, François L Gasse

  • 1Weybridge, VT, USA.

Lancet (London, England)
|September 15, 2007
PubMed
まとめ

妊産婦および新生児のは,特に発展途上国において,世界的に顕著な死亡率を引き起こします. これらの病気を予防するには,広範囲にわたるテタヌス・トキソイドワクチン接種と,長期的な排除のために改善された医療インフラが必要です.

科学分野:

  • 公衆衛生は公衆衛生である.
  • 感染症予防 感染症予防
  • グローバル・ヘルス・セキュリティー グローバル・ヘルス・セキュリティー

背景:

  • 妊産婦と新生児の (MNT) は,世界の妊産婦と新生児の死亡率に大きく貢献しており,毎年約18万人が死亡しており,主に開発途上国で発生しています.
  • テタヌス・トキソイドワクチンによる母体免疫と無菌ケアなどの効果的な予防方法にもかかわらず,MNTは48カ国で,主にアジアとアフリカで,持続的な公衆衛生問題であり続けています.

研究 の 目的:

  • 世界的に,母体および新生児の疹の進行中の負担を強調するために.
  • MNTの撲滅に向けた国々の支援において,母性・新生児性テタヌス撲滅イニシアチブの役割を強調する.
  • 持続的なMNTの撲滅のために,堅牢な医療インフラと普遍的なサービスへのアクセスを必要としていることを強調する.

主な方法:

  • 妊産婦および新生児で発生するテタヌスに関連した世界的な死亡率データに関するレビュー.
  • 母子・新生児チタノスの撲滅イニシアチブで採用されている戦略の説明.
  • MNTの持続に寄与する要因の分析と長期的な排除の要件.

主要な成果:

  • 妊産婦および新生児のは,実質的な死亡率を引き起こし,ほとんどすべての死亡は開発途上国で発生しています.

さらに関連する動画

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
04:18

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice

Published on: October 10, 2025

関連する実験動画

Last Updated: Jul 11, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
04:18

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice

Published on: October 10, 2025

  • 集中治療を施す病院で結核患者の生存率の改善が認められていますが,これらの施設は,高負担地域ではしばしばアクセスできません.
  • 妊産婦と新生児のテタヌス撲滅イニシアチブは,テタヌス・トキソイドワクチン接種を,流行地域における生育年齢の女性たちに提供するために積極的に活動しています.

    • 結論:

    • 究極の目標は,母体および新生児で発生するテタヌスを世界的に撲滅することです.
    • MNTの根絶を継続するには,免疫と医療サービスのインフラストラクチャの改善と,これらのサービスへの普遍的なアクセスが必要です.
    • 妊産婦と幼児の死亡率を減らすための世界的なコミットメントは,長期的にMNTの除去に必要なシステミックな変化を推進することができます.