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Updated: Jul 11, 2026

TRAP-rc, Translating Ribosome Affinity Purification from Rare Cell Populations of Drosophila Embryos
10:26

TRAP-rc, Translating Ribosome Affinity Purification from Rare Cell Populations of Drosophila Embryos

Published on: September 10, 2015

リボソームをトラップして遺伝子発現を制御する.

Daniel Boehringer1, Nenad Ban

  • 1Institute of Molecular Biology and Biophysics, ETH Zurich, CH-8092 Zurich, Switzerland.

Cell
|September 25, 2007
PubMed
まとめ

研究者は,タンパク質合成の調節を理解するために,リボソームの折りたたまれたメッセンジャーRNA (mRNA) 構造を視覚化しました. この研究は,mRNAの自己調節が翻訳開始にどのように影響するかを明らかにしています.

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Using SecM Arrest Sequence as a Tool to Isolate Ribosome Bound Polypeptides09:42

Using SecM Arrest Sequence as a Tool to Isolate Ribosome Bound Polypeptides

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Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
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Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
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Types of RNA01:20

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Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in regulating gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
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