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Updated: Jul 11, 2026

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
14:44

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

設計されたメタロペプチドを使用して,亜鉛指タンパク質にタンパク質が折り畳まれるためのエネルギーコストを引く

Amit R Reddi1, Tabitha R Guzman, Robert M Breece

  • 1Department of Chemistry, Columbia University, New York, NY 10027, USA.

Journal of the American Chemical Society
|October 2, 2007
PubMed
まとめ

亜鉛指タンパク質は,構造と機能のために亜鉛 (II) イオンを使用します. この研究では,亜鉛 ((II) 結合熱力学が異なる調整部位に定量化され,タンパク質の折りたたみと安定性にとって極めて重要なエントロピー主導の複合性を明らかにしています.

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