昼間対夜間走行式血圧の予測精度:コホート研究
José Boggia1, Yan Li, Lutgarde Thijs
1Departamento de Fisiopatología, Hospital de Clínicas, Universidad de la República, Montevideo, Uruguay.
Lancet (London, England)
|October 9, 2007
まとめ
夜間の血圧は,昼間の測定値も考慮したとしても,死亡率の強い予測指標です. 総合的な心血管リスク評価のために,一日中,通行式血圧モニタリングが推奨されます.
科学分野:
- 心臓病学 心臓病学
- 高血圧の研究 高血圧の研究
- 予防医学は,予防的な医療です.
背景:
- 昼間の測定値と比較して夜間の血圧の独立した予測値に関する研究は限られている.
- 夜から昼間の血圧比の予後的意義については,さらなる調査が必要である.
研究 の 目的:
- 昼と夜の両方で,アンブラトリー血圧の予後的意義を評価するために.
- 死亡率と心血管疾患に関する夜間対昼間の血圧比の予測価値を評価する.
主な方法:
- 6カ国の7458人を対象に,24時間通行式血圧モニタリングを実施した.
- 多変数調整された危険比率は,昼間,夜間血圧,シストリック・ナイト・トゥ・デイ比,共変数を制御して計算された.
主要な成果:
- 夜間の血圧は,合計,心血管,心血管以外の死亡率を独立して予測した.
- 昼間の血圧は,夜間の測定値に調整され,心血管以外の死亡率とすべての心血管イベントを予測しました.
- シストリックナイト・トゥ・デイ比が1またはそれ以上であった場合,死亡リスクの増加と関連していました.
結論:
- 昼間の血圧は,夜間の測定値に調整すると,治療中の患者を除いて,心血管疾患の予後値を維持します.
- この発見は,24時間全般のアンブラトリー血圧の定期的な記録を支持する.
- 夜間の高血圧は,逆因果関係を示す可能性があり,さらなる研究が必要である.
関連する概念動画
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