関連する実験動画

Updated: Jun 6, 2026

Visualization of Endoplasmic Reticulum Localized mRNAs in Mammalian Cells
10:24

Visualization of Endoplasmic Reticulum Localized mRNAs in Mammalian Cells

Published on: December 17, 2012

mRNAのローカライゼーションのグローバル分析は,細胞の構造と機能を組織する上で重要な役割を果たしていることを示しています

Eric Lécuyer1, Hideki Yoshida, Neela Parthasarathy

  • 1Banting and Best Department of Medical Research, University of Toronto, Toronto, Canada.

Cell
|October 10, 2007
PubMed
まとめ

ほとんどのタンパク質の局所化は翻訳後に起こりますが,この研究では,発現する遺伝子の71%が初期開発中に局所化されたメッセンジャーRNA (mRNA) があることが明らかになりました. この発見は,mRNAの局所化を強調しています.

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Production of Xenopus tropicalis Egg Extracts to Identify Microtubule-associated RNAs

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Isolation of mRNAs Associated with Yeast Mitochondria to Study Mechanisms of Localized Translation14:44

Isolation of mRNAs Associated with Yeast Mitochondria to Study Mechanisms of Localized Translation

Published on: March 15, 2014

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Chromatin Structure Regulates pre-mRNA Processing02:41

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Ribosome Profiling02:24

Ribosome Profiling

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Regulated mRNA Transport02:22

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Regulation of Expression at Multiple Steps01:23

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The gene expression in cells is regulated at different stages: (i) transcription, (ii) RNA processing, (iii) RNA localization, and (iv) translation. Transcriptional regulation is mediated by regulatory proteins such as transcription factors, activators, or repressors—these control gene expression by initiating or inhibiting the transcription of genes. Once a precursor or pre-mRNA is produced, it undergoes post-transcriptional modification, including 5' capping, splicing, and the addition of a...