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小腸と大腸の幹細胞をマーカー遺伝子Lgr5によって識別する

Nick Barker1, Johan H van Es, Jeroen Kuipers

  • 1Hubrecht Institute, Uppsalalaan 8, 3584CT Utrecht, The Netherlands.

Nature
|October 16, 2007
PubMed
まとめ

研究者らは,腸の幹細胞のマーカーとしてLgr5 (レウシンに富んだ繰り返しを含むGタンパク質結合受容体5) を特定した. クリプトの基底にあるLgr5陽性細胞は,すべての上皮の系統を生成し,その幹細胞の役割を確認する.

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