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Updated: Jun 21, 2026

Murine Model of CD40-activation of B cells
12:24

Murine Model of CD40-activation of B cells

Published on: March 6, 2010

TNFスーパーファミリーメンバーCD40Lのホモトリマーを模倣する小型の多価アーキテクチャ:構造とエフェクタ機能の関係を線引きする

Nathalie Trouche1, Sébastien Wieckowski, Weimin Sun

  • 1Centre National de la Recherche Scientifique, Institut de Biologie Moléculaire et Cellulaire, laboratoire d'Immunologie et Chimie Thérapeutiques, 15 rue René Descartes, 67084 Strasbourg, France.

Journal of the American Chemical Society
|October 16, 2007
PubMed
まとめ

CD40を標的にする合成の多価リガンドは,免疫反応を高めることができます. 最適な設計には,放射分布,C3対称性,および強力なCD40信号伝達および治療用途のための適切なリンク器が含まれています.

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