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ヘリコバクターはインテグリンを利用して,IV型分泌とキナーゼ活性化を行う

Terry Kwok1, Dana Zabler, Sylwia Urman

  • 1Department of Medical Microbiology, Otto von Guericke University, Leipziger Strasse 44, D-39120 Magdeburg, Germany.

Nature
|October 19, 2007
PubMed
まとめ

Helicobacter pyloriは,CagLタンパク質を使用してインテグリンα5β1を活性化し,CagAオンコタンパク質を胃細胞に注入します. これは,H. pyloriの病原化と癌の発症における重要なメカニズムを明らかにしています.

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