関連する実験動画

Updated: Jul 10, 2026

Optimized Negative Staining: a High-throughput Protocol for Examining Small and Asymmetric Protein Structure by Electron Microscopy
09:37

Optimized Negative Staining: a High-throughput Protocol for Examining Small and Asymmetric Protein Structure by Electron Microscopy

Published on: August 15, 2014

異なるアポリポプロテインは,ナノリポプロテイン粒子の形成に影響を与えます

Brett A Chromy1, Erin Arroyo, Craig D Blanchette

  • 1Chemistry, Materials, and Life Sciences, Lawrence Livermore National Laboratory, Livermore, California 94551, USA.

Journal of the American Chemical Society
|October 30, 2007
PubMed
まとめ

研究者は,様々なアポリポタンパク質とフォスフォリピドを使用して,ナノリポタンパク質粒子 (NLP) を作成しました. これらのNLPは生物学的膜を模倣し,使用された特定のアポリポタンパク質に基づいてサイズが異なります.

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Formulation and Characterization of Bioactive Agent Containing Nanodisks

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Click-Chemistry Based Fluorometric Assay for Apolipoprotein N-acyltransferase from Enzyme Characterization to High-Throughput Screening07:37

Click-Chemistry Based Fluorometric Assay for Apolipoprotein N-acyltransferase from Enzyme Characterization to High-Throughput Screening

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Overview
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Regulation of Nuclear Protein Sorting

Nuclear protein sorting regulates nucleus composition and gene expression, crucial for determining the fate of a eukaryotic cell. Hence, the entry and exit of molecules across the nuclear envelope is a tightly controlled process. Nuclear protein sorting can be inhibited by one of the following ways: 1) masking cargo signal sequences, 2) modifying the nuclear receptor's affinity for cargo, 3) controlling the nuclear pore size, 4) retaining the cargo during its transit to the cytosol or the...
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Lipid-derived Compounds in the Human Body

Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various  biological processes .
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Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin, delayed...
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Drug binding to proteins is a key aspect of pharmacokinetics and can influence a drug's distribution, absorption, and elimination in the body. Several factors, including the drug's physiochemical properties, protein concentration, disease states, and the number of binding sites on the protein, influence this process.
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Mechanisms of Membrane Domain Formation

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