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Updated: Jul 10, 2026

Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers
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Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers

Published on: September 19, 2022

ミニチュアタンパク質は,最小のカチオンのPPIIモチーフを基に,内在的に細胞に浸透します

Douglas S Daniels1, Alanna Schepartz

  • 1Department of Chemistry, Yale University, New Haven, Connecticut 06520-8107, USA.

Journal of the American Chemical Society
|November 7, 2007
PubMed
まとめ

研究者は,ユニークなポリプロリンII (PPII) 螺旋構造を持つ新しい細胞浸透ペプチド (CPPs) を開発しました. これらのCPPは,優れた細胞吸収効率と低細胞毒性を実証し,分子配送技術の有望な進歩を提供します.

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