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Updated: May 2, 2026

Patch Clamp and Perfusion Techniques for Studying Ion Channels Expressed in Xenopus oocytes
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トランスジェニックマウスのアルドステロン誘発冠動脈機能障害は,血管の滑らかな筋肉細胞のカルシウム活性化カリウム (BKCa) チャンネルを巻き込む

Marie-Lory Ambroisine1, Julie Favre, Patricia Oliviero

  • 1Inserm U689 and Paris Diderot University, Paris, France.

Circulation
|November 7, 2007
PubMed
まとめ

マウスにおけるアルドステロンの過剰発現は,血管内のカルシウム活性化カリウム (BKCa) 経路を減少させ,冠動脈のリラックスを損なう. これは,BKCaチャネルが心血管疾患の潜在的な治療標的であることを示唆しています.

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