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Updated: Jul 10, 2026

A High-Throughput Comet Assay Approach for Assessing Cellular DNA Damage
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A High-Throughput Comet Assay Approach for Assessing Cellular DNA Damage

Published on: May 10, 2022

シスプラチンによる抗がん治療中に発生したDNA病変のバイパスは,DNAポリメラーゼエタによって行われます

Aaron Alt1, Katja Lammens, Claudia Chiocchini

  • 1Munich Center for Integrated Protein Science (CiPS), Ludwig Maximilians University, D-81377 Munich, Germany.

Science (New York, N.Y.)
|November 10, 2007
PubMed
まとめ

DNAポリメラーゼエタ (Pol eta) は,シスプラチン添加物や紫外線誘発型チミンジマーなどのDNA病変に複製します. 構造分析は,Pol eta がどのように機能しているかを明らかにします.

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