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Updated: Jul 10, 2026

Development and Application of Rapamycin-regulated Tyrosine Phosphatases
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Rhebは,mTORの内生性阻害剤であるFKBP38を反抗することによってmTORを活性化します

Xiaochun Bai1, Dongzhu Ma, Anling Liu

  • 1Department of Pharmacology, University of Pittsburgh School of Medicine, E1357 Biomedical Science Tower, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

Science (New York, N.Y.)
|November 10, 2007
PubMed
まとめ

ラパミシン (mTOR) の哺乳類の標的は細胞の成長を制御し,Rheb.によって調節されます. Rhebは,FKBP38がmTORを阻害することを防止し,細胞成長のための新しい規制経路を明らかにします.

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