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Updated: Apr 30, 2026

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes
10:05

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes

Published on: August 13, 2012

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腸内皮質におけるcAMPトランスポーターとCFTR塩化物チャネル機能の空間時間的結合

Chunying Li1, Partha C Krishnamurthy, Himabindu Penmatsa

  • 1Department of Physiology, The University of Tennessee Health Science Center, 894 Union Avenue, 420 Nash, Memphis, TN 38163, USA.

Cell
|November 30, 2007
PubMed
まとめ

多剤耐性タンパク質4 (MRP4) は,cAMPトランスポーターであり,システィック線維症のトランスメブラン伝導性調節器 (CFTR) と物理的にも機能的にも関連しています. MRP4を阻害すると,CFTRの機能が強化され,分泌性下痢から保護されます.

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