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Updated: Jul 9, 2026

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness
06:21

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness

Published on: May 7, 2018

単一の残留スイッチでアビエタディエン合成酵素をピマラディエン固有のサイクラースに変換します

P Ross Wilderman1, Reuben J Peters

  • 1Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA.

Journal of the American Chemical Society
|December 7, 2007
PubMed
まとめ

アビエタディエン合成酵素で単一のアミノ酸を変化させると,複雑なサイクル反応をリダイレクトし,異なるディターペン製品を生成することができます. この発見は,テルペン合成酵素のメカニズムとエンジニアリングの可能性についての洞察を提供します.

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A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

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Retropinacol/Cross-pinacol Coupling Reactions - A Catalytic Access to 1,2-Unsymmetrical Diols

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Diels–Alder Reaction Forming Cyclic Products: Stereochemistry

The Diels–Alder reaction is one of the robust methods for synthesizing unsaturated six-membered rings. The reaction involves a concerted cyclic movement of six π electrons: four π electrons from the diene and two π electrons from the dienophile.
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Characteristics of the diene
Conformation
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