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Updated: Jul 9, 2026

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050
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ベータアミノ酸生物合成におけるMIOベースのアミノムタゼのメカニズム

Carl V Christianson1, Timothy J Montavon, Grace M Festin

  • 1Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, USA.

Journal of the American Chemical Society
|December 7, 2007
PubMed
まとめ

アロマティックベータアミノ酸は,4-メチリデニミダゾール-5-オン (MIO) 酵素を用いて合成されます. この研究では,MIOは,アミノミューターゼ酵素におけるアンモニアの直接移転に基質アミンアダクト経由の共振触媒を用いていることが明らかになりました.

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