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Updated: Jul 9, 2026

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
09:51

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

Published on: July 26, 2017

TAMperingは,トール型受容体シグナル伝達によるタッパーリングである

Luke A J O'Neill1

  • 1School of Biochemistry and Immunology, Trinity College, Dublin 2, Ireland. laoneill@tcd.ie

Cell
|December 18, 2007
PubMed
まとめ

ホストの防御に不可欠なトール型受容体 (TLR) 信号伝達は,自己免疫疾患を予防するために厳格に規制されています. 新しい研究では,Tyro3/Axl/Mer受容体チロシンキナーゼが負のフィードバックメカニズムとして作用し,SOCSタンパク質発現を促進することによってTLR誘発の炎症を抑制することを明らかにしています.

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Detection of Neu1 Sialidase Activity in Regulating TOLL-like Receptor Activation09:04

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A Macrophage Reporter Cell Assay to Examine Toll-Like Receptor-Mediated NF-kB/AP-1 Signaling on Adsorbed Protein Layers on Polymeric Surfaces07:55

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