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Updated: Jul 9, 2026

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
14:55

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy

Published on: September 17, 2017

化学的シフトの混乱を用いた急速なタンパク質-リガンド構造

Jaime Stark1, Robert Powers

  • 1Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588, USA.

Journal of the American Chemical Society
|December 20, 2007
PubMed
まとめ

この研究は,NMR化学シフト扰乱 (CSP) データを用いてタンパク質-リガンド構造を決定するためのより速い方法を導入しています. このアプローチは,構造ベースの薬剤設計における分子ドッキングの精度を向上させます.

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