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Updated: May 12, 2026

MicroRNA-based Regulation of Picornavirus Tropism
09:05

MicroRNA-based Regulation of Picornavirus Tropism

Published on: February 6, 2017

RNA結合タンパク質Dnd1は,マイクロRNAがターゲットmRNAへのアクセスを阻害する

Martijn Kedde1, Markus J Strasser, Bijan Boldajipour

  • 1The Netherlands Cancer Institute, Division of Tumor Biology, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands.

Cell
|December 25, 2007
PubMed
まとめ

RNA結合タンパク質であるデッドエンド1 (Dnd1) は,マイクロRNA (miRNA) の抑制からメッセンジャーRNA (mRNA) を保護する. Dnd1は尿素に富んだ領域に結合し,miRNAが遺伝子発現を阻害するのを防ぐことで,新しい調節機構を明らかにします.

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Molecular Modulation by Lentivirus-Delivered Specific shRNAs in Endoplasmic Reticulum Stressed Neurons10:50

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RNA Interference01:23

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RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
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MicroRNAs01:22

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