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Updated: Jan 28, 2026

Ultra-long Read Sequencing for Whole Genomic DNA Analysis
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Ultra-long Read Sequencing for Whole Genomic DNA Analysis

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ゲノム疾患に関連する非再発的な再編成を生成するためのDNA複製メカニズム

Jennifer A Lee1, Claudia M B Carvalho, James R Lupski

  • 1Department of Molecular and Human Genetics, Baylor College of Medicine, Houston TX, 77030, USA.

Cell
|December 28, 2007
PubMed
まとめ

新しい複製ベースのメカニズムであるフォーク・スタリング・アンド・テンプレート・スイッチング (FoSTeS) は,ペリザエウス・メルズバッハ病 (PMD) の複雑なゲノム再編成を説明する可能性がある. このメカニズムは,従来の再結合モデルを超えて,不定期的な再配置に関する洞察を提供します.

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