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Updated: Jul 8, 2026

Purification of Hsp104, a Protein Disaggregase
07:17

Purification of Hsp104, a Protein Disaggregase

Published on: September 30, 2011

非典型的なAAA+サブユニットパッキングは,タンパク質再構成因子Hsp104による分解のための拡張した空洞を作り出します

Petra Wendler1, James Shorter, Celia Plisson

  • 1Department of Crystallography, Birkbeck College, Malet Street, London WC1E 7HX, UK.

Cell
|December 28, 2007
PubMed
まとめ

熱ショックタンパク質104 (Hsp104) は,細胞がストレスから回復するのを助けるためにタンパク質を分解します. Cryo-EMによって明らかになったそのユニークな構造は,コイルドコイルドメインがタンパク質抽出とATP水解の鍵であることを示している.

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