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Updated: Jul 8, 2026

Real-time Imaging of Myeloid Cells Dynamics in ApcMin/+ Intestinal Tumors by Spinning Disk Confocal Microscopy
05:21

Real-time Imaging of Myeloid Cells Dynamics in ApcMin/+ Intestinal Tumors by Spinning Disk Confocal Microscopy

Published on: October 6, 2014

トライソミーは,ダウン症候群のマウスモデルにおけるApc (Min) 媒介の腫瘍を抑制する

Thomas E Sussan1, Annan Yang, Fu Li

  • 1Department of Physiology and The Institute for Genetic Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

Nature
|January 4, 2008
PubMed
まとめ

ダウン症候群 (トリソミー21) の個人は,腸内腫瘍の発生率が低い可能性があります. マウスモデルでは,特にEts2遺伝子が関わるトライソミーは,腫瘍の発症を大幅に減少させ,潜在的な予防効果を示唆していることが示されています.

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A Non-random Mouse Model for Pharmacological Reactivation of Mecp2 on the Inactive X Chromosome08:27

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