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Updated: May 1, 2026

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1
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Published on: February 18, 2011

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BRCA1/2キャリアの乳がんリスクの変動

Colin B Begg1, Robert W Haile, Ake Borg

  • 1Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA. beggc@mskcc.org

JAMA
|January 10, 2008
PubMed
まとめ

乳がんのリスクは,BRCA1およびBRCA2変異のキャリアによって著しく異なります. この変動は,観察可能な要因を考慮しても存在し,遺伝性乳がんにおける個別化されたリスク評価の必要性を強調しています.

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