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関連する概念動画

Frequency-dependent Selection01:21

Frequency-dependent Selection

When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.Positive Frequency-Dependent SelectionIn positive...
Dosage Compensation02:50

Dosage Compensation

In animals, gender is determined by the number and type of sex chromosome. For example, human females have two X chromosomes, and males have one X and one Y chromosome, whereas C.elegans with one X chromosome is a male, and the one with two X chromosomes is a hermaphrodite.
In addition to sexual development, the X chromosome has genes involved in autosomal functions such as brain development and the immune system. Therefore, males and females with  distinct numbers of X chromosomes will have...
Types of Selection01:46

Types of Selection

Natural selection influences the frequencies of particular alleles and phenotypes within populations in several different ways. Primarily, natural selection can be directional, stabilizing, or disruptive. Directional selection favors one extreme trait and shifts the population towards that phenotype while selecting against individuals displaying alternate traits. Stabilizing selection favors an intermediate trait with a narrow range of variation. Deviation from the optimal phenotype towards an...

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Natural variation suggests candidate genes underlying Caenorhabditis elegans susceptibility to diverse toxicants.

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関連する実験動画

Updated: Jul 8, 2026

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
06:18

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

Published on: July 11, 2025

C. elegansにおける広範な遺伝的不適合性は,バランシング・セレクションによって維持された.

Hannah S Seidel1, Matthew V Rockman, Leonid Kruglyak

  • 1Lewis-Sigler Institute for Integrative Genomics and Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA. hseidel@princeton.edu

Science (New York, N.Y.)
|January 12, 2008
PubMed
まとめ

遺伝的不適合性は,通常,自然選択によって排除されます. しかし,Caenorhabditis elegansの研究では,持続的な不適合性が発見され,バランスのとれたポリモルフィズムがこの遺伝的対立を維持することを示唆しました.

科学分野:

  • 進化遺伝学の進化遺伝学について
  • 集団遺伝学 人口遺伝学
  • 分子生物学は分子生物学である.

背景:

  • 自然選択は,交配する集団の間の遺伝的相容れないものを通常除去する.
  • 遺伝的不適合は,生物の健康に悪影響を及ぼす可能性があります.

研究 の 目的:

  • 世界的に分布しているCaenorhabditis elegans.の遺伝的不適合性を調査する.
  • フィットネスコストにもかかわらず,この不適合性を維持する進化的メカニズムを理解するために.

主な方法:

  • リンクされたロシ zeel-1とpeel-1の集団遺伝分析.
  • 配列の逸脱とリンクの不均衡の検討.
  • 適合性の不一致による健康上の影響を評価する.

主要な成果:

  • zeel-1とpeel-1のアレル間の特定の不適合性が特定されました.
  • 互換性のないアレルは密接に結びつき,共通のハプロタイプに見られます.
  • 自然選択は,これらのハプロタイプを積極的に保存し,不適合性を維持します.

結論:

さらに関連する動画

Manipulation of Ploidy in Caenorhabditis elegans
07:54

Manipulation of Ploidy in Caenorhabditis elegans

Published on: March 15, 2018

Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism
11:20

Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism

Published on: December 11, 2009

関連する実験動画

Last Updated: Jul 8, 2026

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
06:18

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

Published on: July 11, 2025

Manipulation of Ploidy in Caenorhabditis elegans
07:54

Manipulation of Ploidy in Caenorhabditis elegans

Published on: March 15, 2018

Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism
11:20

Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism

Published on: December 11, 2009

  • リンクされた局所を含むバランスの取れたポリモルフィズムは,Caenorhabditis elegans.の遺伝的不適合性を保持します.
  • このバランスのとれた多形性は,遺伝子フローと健康への悪影響にもかかわらず持続する.