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Updated: Jul 8, 2026

Systems Biology of Metabolic Regulation by Estrogen Receptor Signaling in Breast Cancer
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Systems Biology of Metabolic Regulation by Estrogen Receptor Signaling in Breast Cancer

Published on: March 17, 2016

H3K9me2脱メチル化によって引き起こされるDNA酸化は,エストロゲン誘発遺伝子発現を駆動する

Bruno Perillo1, Maria Neve Ombra, Alessandra Bertoni

  • 1Istituto di Scienze dell'Alimentazione, Consiglio Nazionale delle Ricerche (C.N.R.), 83100 Avellino, Italy. perillo@unina.it

Science (New York, N.Y.)
|January 12, 2008
PubMed
まとめ

ヒストンの改変が遺伝子発現を誘導する. LSD1によって誘発されるエストロゲン受容体標的のH3ライシン9脱メチル化は,DNA修復経路を開始し,エストロゲン誘発転写を可能にします.

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Profiling of Estrogen-regulated MicroRNAs in Breast Cancer Cells

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X-chromosome...
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