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Updated: May 17, 2026

Measuring Nucleotide Binding to Intact, Functional Membrane Proteins in Real Time
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ゲーティング時に単分子KcsAカリウムチャネルのグローバル回転運動

Hirofumi Shimizu1, Masayuki Iwamoto, Takashi Konno

  • 1CREST Sasaki-team, Japan Science and Technology Corporation, Tachikawa, Tokyo, 190-0012, Japan.

Cell
|January 15, 2008
PubMed
まとめ

研究者らは,イオンチャネルゲーティング中にKcsAカリウムチャネルがねじれることを観察しました. ドメイン間のこの機械的な歪みは,特定のイオンチャネルブロッカーによってブロックされました.

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