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Updated: Jul 8, 2026

Visualization of Endoplasmic Reticulum Subdomains in Cultured Cells
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誤った折りたたまれたポリトピック膜タンパク質のER関連分解を剖析する

Kunio Nakatsukasa1, Gregory Huyer, Susan Michaelis

  • 1Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA.

Cell
|January 15, 2008
PubMed
まとめ

チャペロンは,エンドプラズマ網膜関連分解 (ERAD) を通して,誤った折りたたまれた膜タンパク質の分解を積極的に支援します. ポリユビキチネーションとCdc48複合体は,これらのタンパク質を破壊するためにERから抽出するために不可欠です.

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