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Updated: Jun 30, 2026

The Sciatic Nerve Cuffing Model of Neuropathic Pain in Mice
07:09

The Sciatic Nerve Cuffing Model of Neuropathic Pain in Mice

Published on: July 16, 2014

特定の脊髄GABAA受容体のサブタイプを通じた病理的な痛みの逆転

Julia Knabl1, Robert Witschi, Katharina Hösl

  • 1Institute of Experimental and Clinical Pharmacology and Toxicology, University of Erlangen-Nürnberg, D-91054 Erlangen, Germany.

Nature
|January 19, 2008
PubMed
まとめ

薬剤L-838,417で特定の脊髄GABA (A) 受容体をターゲットにすることで,慢性炎症性および神経疾患の痛みを効果的に治療します. このアプローチは鎮静剤や運動障害なしに強力な鎮痛作用を提供し,新しい痛み療法への道を開く.

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Identification and Classification of Position-specific GABAA Receptor Subunit Missense Variants for Their Role In Hippocampal Pyramidal Neurons08:04

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