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ユカリオットにおけるイントロンスプライシングの翻訳制御

Olivier Jaillon1, Khaled Bouhouche, Jean-François Gout

  • 1Genoscope (CEA), 2 rue Gaston Crémieux CP5706, 91057 Evry, France.

Nature
|January 19, 2008
PubMed
まとめ

ユカリオット遺伝子はイントロンを除去するためにスプライシングを使用しますが,精度は依然として課題です. この研究は,ナンセンス媒介型mRNA衰退 (NMD) が,特にイントロンが多い種において,欠陥トランスクリプトを退廃させることで,適切な遺伝子発現を確保するのに役立つことを明らかにしています.

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