幼児期から成人期までの死亡率と早産の続変の概要
1Department of Paediatrics, McMaster University, Hamilton, ON, Canada. saigal@mcmaster.ca
Lancet (London, England)
|January 22, 2008
まとめ
時期尚早に生まれた乳児は,発達や行動に関する問題を含む長期的な健康リスクに直面します. しかし,ほとんどの非常に早産児は成人期に順調に適応し,脳損傷などの合併症を予防することに焦点を移します.
科学分野:
- 新生児医学 新生児医学
- 発達小児科 発達小児科
- 産経周りの健康について
背景:
- 生命力の限界の乳児の生存率は著しく改善しました.
- 生存率が向上したにも関わらず,早産児は短期的および長期的に深刻な病気に直面しています.
- 発症率は妊娠年齢と逆相関しており,妊娠年齢が完全にリスクから除外されるわけではありません.
研究 の 目的:
- 胎児における合併症のスペクトルを強調するために.
- 長期的な罹病率の低減と脳損傷の予防に向けた焦点転換を強調する.
- 心血管疾患や代謝障害などの後期のリスクを特定するための継続的なフォローアップを提唱する.
主な方法:
- 早産児のアウトカムに関する既存の文献のレビュー.
- 妊娠年齢に関連する罹病率パターンの分析.
- 成人期までの早産生存者の縦断的な観察.
主要な成果:
- 胎児は神経発達障害を患い,幼児期に再発する健康問題を経験します.
- 学習や行動の問題などの隠された障害は,青春期に現れる.
- 大半の非常に早産の生存者は,成人への移行期間中に順調に適応します.
結論:
- 死亡率の低減は,長期的な発病率,特に脳損傷の予防に重点を置くことを必要としています.
- 早期生存者の心血管疾患や代謝障害のリスクを特定するために,長期的なフォローアップは極めて重要です.
- 産前期介入の戦略は,早産児の全般的な健康ニーズに対処するために,その生涯を通じて進化する必要があります.
関連する概念動画
Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Pathophysiology of Diabetes
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Socioemotional Development during Infancy
Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types
Stella Chess...
Primary Temperament Types
Stella Chess...
Development of Human Microbiota
The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
Development of the Oral Microbiota
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
Introduction to Language of Pathophysiology ll
This lesson explores key terms that describe how diseases progress, their outcomes, and their distribution in populations.Diagnostic tests identify diseases and monitor treatment. These include blood and urine tests, biopsies, imaging (X-ray, MRI), and detection of infectious agents.Remission is a reduction or disappearance of symptoms.Exacerbation refers to the worsening of symptoms, such as increased wheezing during an asthma attack.A precipitating factor triggers an acute episode, while a...


