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Updated: Jul 8, 2026

Rapid Synthesis and Screening of Chemically Activated Transcription Factors with GFP-based Reporters
09:22

Rapid Synthesis and Screening of Chemically Activated Transcription Factors with GFP-based Reporters

Published on: November 26, 2013

トランスクリプションアクティベーターが内生プロモーターで同時に高速と遅いサイクルを繰り返す

Tatiana S Karpova1, Min J Kim, Corentin Spriet

  • 1Center for Cancer Research Core Imaging Facility, Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, National Institutes of Health, 41 Library Drive, Bethesda, MD 20892, USA.

Science (New York, N.Y.)
|January 26, 2008
PubMed
まとめ

速くて遅いトランスクリプションアクティベーターサイクルは,酵母プロモーターで発生します. 遅いサイクルはmRNAの量を調節し,速いサイクルは転写を開始し,以前の見解に異議を唱えます.

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Real-time Analysis of Transcription Factor Binding, Transcription, Translation, and Turnover to Display Global Events During Cellular Activation12:54

Real-time Analysis of Transcription Factor Binding, Transcription, Translation, and Turnover to Display Global Events During Cellular Activation

Published on: March 7, 2018

Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models13:47

Lentiviral Vector Platform for the Efficient Delivery of Epigenome-editing Tools into Human Induced Pluripotent Stem Cell-derived Disease Models

Published on: March 29, 2019

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RNA Polymerase II Accessory Proteins

Proteins that regulate transcription can do so either via direct contact with RNA Polymerase or through indirect interactions facilitated by adaptors, mediators, histone-modifying proteins, and nucleosome remodelers. Direct interactions to activate transcription is seen in bacteria as well as in some eukaryotic genes. In these cases, upstream activation sequences are adjacent to the promoters, and the activator proteins interact directly with the transcriptional machinery. For example, in...
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The binding domains are capable of recognizing and interacting with regulatory sequences on the DNA. These domains are...
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Co-activators and Co-repressors

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Co-activators and Co-repressors02:04

Co-activators and Co-repressors

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