ウスティロキシン天然製品およびそのアナログの総合合成の進化

Pixu Li1, Cory D Evans, Yongzhong Wu

  • 1Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania 19104, USA.

まとめ

研究者らは,強力な抗真菌性サイクロペプチドであるウスティロキシンDとFを合成した. C-9メチラミノ群とフェノルヒドロキシルを含む主要な構造特性は,チューブリンポリメリゼーションを抑制するために重要である.

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