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静脈血栓塞栓症のリスクと急性病院での予防 (ENDORSE研究):多国籍の横断研究
Alexander T Cohen1, Victor F Tapson, Jean-Francois Bergmann
1King's College Hospital, London, UK. alexander.cohen@kcl.ac.uk
Lancet (London, England)
|February 5, 2008
まとめ
静脈性血栓塞栓症 (VTE) は,リスクの高い病院患者の半数以上に影響しますが,適切な予防法は,世界的に十分に活用されていません. これは,世界中の病院で体系的なVTEリスク評価と予防戦略の必要性を強調しています.
科学分野:
- クリニカル・メディシン 臨床医学
- エピデミオロジー エピデミオロジー
- 公衆衛生は公衆衛生である.
背景:
- 静脈血栓塞栓症 (VTE) は,入院患者にとって重大なリスクをもたらします.
- VTEリスクの変動と予防療法に関する世界的なデータは限られている.
- ENDORSEの研究は,この知識のギャップを埋めることを目的とした.
研究 の 目的:
- 病院での急性治療におけるVTEリスクの世界的な流行を評価する.
- 有効なVTE予防療法を受けているリスクのある患者の割合を決定する.
- 確立されたVTE予防ガイドラインの遵守を評価する.
主な方法:
- 32カ国の358の病院を対象とした多国籍の横断調査です.
- 入会基準:40歳以上の医療入院患者,18歳以上の外科入院患者.
- 2004年アメリカ胸科医師会 (ACCP) のガイドラインを用いて評価されたVTEリスクと予防の適切性.
主要な成果:
- 68,183人の患者が登録され,51.8%がVTEのリスクがあると特定されました.
- 手術を受けた患者 (64.4%) のVTEリスクは,医療従事者 (41.5%) と比べて高かった.
- 適切なVTE予防は,リスクの高い外科患者の58.5%とリスクの高い医療患者の39.5%が受けました.
結論:
- 病院に入院している患者のかなりの割合は,VTEのリスクがあります.
- 適切なVTE予防の割合は,特に医療従事者の間で低いままです.
- VTEリスク評価と予防のための病院全体の戦略は極めて重要です.
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