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Updated: Jul 7, 2026

Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells
09:16

Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells

Published on: September 1, 2019

細胞毒性T細胞発達におけるRunx複合体による転写因子Th-POKの抑制

Ruka Setoguchi1, Masashi Tachibana, Yoshinori Naoe

  • 1Laboratory for Transcriptional Regulation, RIKEN Research Center for Allergy and Immunology, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan.

Science (New York, N.Y.)
|February 9, 2008
PubMed
まとめ

Runx転写因子は,Th-POK発現を抑制することによって,Tヘルパー細胞の発達を積極的に阻害する. これにより,適応免疫に不可欠なCD8+細胞毒性T細胞の分化が可能になります.

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Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry

Published on: May 17, 2016

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