選択性イチーター変異体は,社会的アメーバの協力の遺伝的複雑さを明らかにする
Lorenzo A Santorelli1, Christopher R L Thompson, Elizabeth Villegas
1Department of Ecology and Evolutionary Biology, Rice University, Houston, Texas 77005, USA.
Nature
|February 15, 2008
まとめ
進化における協力は",詐欺師"の変異体に対して脆弱である. 社会性アメーバの全ゲノムスクリーンは,浮気に関連する100以上の遺伝子を明らかにし,多くは選択的に行動しています.
科学分野:
- 進化生物学の進化生物学について
- 遺伝学 遺伝学とは
- 社会的行動 社会的行動
背景:
- 協力は,多細胞性やeusocialityのような主要な進化的移行に不可欠です.
- 協力体制の安定性は,協力関係を利用して貢献しない"詐欺師"変異体の出現によって脅かされている.
- 変異体が非親族を欺くが親族と協力する選択的な浮気は,協力を維持することができる.
研究 の 目的:
- 浮気の遺伝的根拠について,ゲノムスケールでの調査を行うため.
- 浮気行動を可能にする遺伝子や遺伝経路を特定する.
- 社会的な有機体における欺瞞の遺伝的機会の流行と性質を理解する.
主な方法:
- 社会的なアメーバモデルシステムで全ゲノムスクリーンを実行しました.
- 浮気フェノタイプを与える突然変異は,生物のゲノム全体で特定されました.
- 浮気行動は,キメリックとクローンコンテキストで評価されました.
主要な成果:
- 様々なタイプの100以上の遺伝子が,浮気と関連していることが判明しました.
- 識別された多くのチーターミュータントは,クローングループで協力するが,キメラで作弊する,学術的な作弊を示した.
- これは,ゲノム全体のスケールで欺くための多面的な遺伝的機会を明らかにします.
結論:
- フェノタイプ的に安定した協同システムには,遺伝的対立が潜んでいる可能性があります.
- 浮気の遺伝的構造は複雑で,数多くの遺伝子や経路が関与しています.
- 進化的衝突と対抗の機会は,社会的相互作用に関与する複数の遺伝子の選択を促す可能性があります.
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