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Updated: Jul 7, 2026

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ミトコンドリア疾患のマウスモデルは,重度のmtDNA変異に対する生殖線選択を明らかにしています

Weiwei Fan1, Katrina G Waymire, Navneet Narula

  • 1Center for Molecular and Mitochondrial Medicine and Genetics, University of California, Irvine, CA 92697, USA.

Science (New York, N.Y.)
|February 16, 2008
PubMed
まとめ

重度のミトコンドリアDNA (mtDNA) 変異は,女性の生殖系から排除されます. 軽度のmtDNA変異は世代を超えて持続し,病気を引き起こすが,人口レベルでの影響にはならない.

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