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Updated: Jun 21, 2026

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ParlによるHtrA2のHx1媒介処理は,リンパ球とニューロンの生存を可能にします

Jyh-Rong Chao1, Evan Parganas, Kelli Boyd

  • 1Department of Biochemistry, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

Nature
|February 22, 2008
PubMed
まとめ

Hax1タンパク質は,免疫細胞と神経細胞のプログラム細胞死 (アポトーシス) を防ぐ. ミトコンドリアのプロテアゼParlとHtrA2と相互作用して,サイトカインシグナル伝達が低いときに細胞生存を維持します.

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