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Updated: Jul 7, 2026

Preparation of Neutrally-charged, pH-responsive Polymeric Nanoparticles for Cytosolic siRNA Delivery
09:09

Preparation of Neutrally-charged, pH-responsive Polymeric Nanoparticles for Cytosolic siRNA Delivery

Published on: May 2, 2019

ポリケーションに生命を吹き込む:pH反応性エンドソモリチスペプチドとポリエチレングリコールによる機能化は,siRNA配送を可能にします

Martin Meyer1, Alexander Philipp, Reza Oskuee

  • 1Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig-Maximilians-Universität München, Germany.

Journal of the American Chemical Society
|February 22, 2008
PubMed
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No abstract available in PubMed .

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Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...