関連する実験動画

Updated: Jul 7, 2026

Genome-wide Screen for miRNA Targets Using the MISSION Target ID Library
08:40

Genome-wide Screen for miRNA Targets Using the MISSION Target ID Library

Published on: April 6, 2012

Lin28によるマイクロRNA処理の選択的ブロック

Srinivas R Viswanathan1, George Q Daley, Richard I Gregory

  • 1Stem Cell Program, Children's Hospital Boston, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA 02115, USA.

Science (New York, N.Y.)
|February 23, 2008
PubMed
まとめ

Lin28タンパク質は,胚細胞におけるlet-7マイクロRNA (miRNA) の処理を阻害する. この発見は,Lin28がmiRNA生殖の負の調節体であり,幹細胞の分化と癌に影響を与えることを示しています.

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Biotin-based Pulldown Assay to Validate mRNA Targets of Cellular miRNAs11:00

Biotin-based Pulldown Assay to Validate mRNA Targets of Cellular miRNAs

Published on: June 12, 2018

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