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Updated: Jul 7, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

複雑なピロリジン合成のためのステレオダイバーゲントの方法論

Stephen K Jackson1, Avedis Karadeolian, Alex B Driega

  • 1Department of Chemistry, The University of Western Ontario, 1151 Richmond Street, London, Ontario, Canada N6A 5B7.

Journal of the American Chemical Society
|February 29, 2008
PubMed
まとめ

この研究では,オキシムエーテルとサイクロプロパンダイステルからピロロ-イソキサゾリジンの二重選択合成を詳細に説明しています. この方法は,薬化学における重要な構成要素である高度に置換されたホモキラルピロリジンへの予測可能なアクセスを可能にします.

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