関連する実験動画

Updated: Jun 19, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
09:04

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells

Published on: May 22, 2014

デンドリット細胞のPAR1-S1P3シグナリングカップルは,凝結と炎症をシグナリングする

Frank Niessen1, Florence Schaffner, Christian Furlan-Freguia

  • 1Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA.

Nature
|February 29, 2008
PubMed
まとめ

セプシスの凝結と炎症は,タンパク質酵素活性化受容体1 (PAR1) とスフィンゴシン1リン酸受容体3 (S1P3) が, dendritic 細胞で信号を送っている. このクロストークを阻害すると,全身の炎症と致死率が低下します.

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